• Paper July 30, 2024 Published an review article about hypoimmune engineering cell therapy in Nature Reviews Bioengineering.
  • Event July 10-13, 2024 Hotta presented at 2024 New Directions in Biology and Disease of Skeletal Muscle Conference @Ft.Lauderdale
  • Staff July 8, 2024 Dongyang Li joined T-CiRA project at Shonan iPark
  • Staff July 1, 2024 Samuel joined the lab as CiRA Research internship student
  • Event June 17-19, 2024 Koji gave a symposium presentation at the 9th JSGE annual meeting @Osaka.
  • Staff June 3, 2024 Ting joined the lab as a postdoc researcher. A summer internship student Tyler also joined through the MIT-Japan program.
  • Event May 11-12, 2024 Hotta gave a presentation at a joint meeting of the Japan Muscle Society, Japan Society for Bone and Mineral Research, and Japan College of Rheumatology.
  • Event May 11, 2024 CiRA Graduate School information session was held.
  • Paper Apr 10, 2024 Joseph's paper on the application of NanoMEDIC technology to investigate the activity of antibody drugs against the SARS-CoV-2 variants is published in Virology.
  • Staff Apr 1, 2023 Yuqin Feng entered the Graduate course at the Faculty of Medicine.
  • Award Nov 29-30, 2023 Dr. Kojima received the Poster Award at the CiRA 2023 International Symposium. Congratulations!
  • Event Nov 16, 2023 AMED-KHIDI Japan-Korea Joint Symposium on Translational Research in Regenerative Medicine and Genome Editing"(AMED website) was held at Nihonbashi Life Science Building in Tokyo.
  • Staff Nov 16, 2022 Yukie Kumeta joined the lab as technical staff.
  • Paper Nov 2, 2023 Preview article published in Cell Stem Cell.
  • Media Aut 26, 2023 Our paper was featured in the EureAlert (AAAS) and GEN (Genetic Engineering & Biotechnology News)!
  • Paper Aug 25, 2023 Yuto's paper was published in Stem Cell Reports.
  • Staff Aug 1, 2023 Research Student Yuqin Feng joined the lab.
  • Event July 18, 2023 Rare Disease Consortium Japan (RDCJ) Inaugural Symposium was held at Shonan iPark
  • Event June 14-17, 2023 ISSCR 2023 @Boston
  • Staff June 6-July 31, 2023 Amgen Scholars Kensho Gendzwill from University of Washington joined Hotta lab
  • Event June 6-8, 2023年 8th Annual meeting of Japanese Society for Genome Editing @Hunabori, Tokyo
  • Event May 16-20, 2023 ASGCT 2023 @Los Angeles
  • Event April 23, 2023 Hotta presented at the 31st General Assembly of the Japan Medical Congress
  • Staff April 11, 2022 Technical staff Yumi Tsubokura joined the lab.
  • Staff April 3, 2022 M.Sci. student Jason Choi joined the lab.
  • Recruitment Feb 9, 2023 We are recruiting a Postdoc, who is interested in the integration of iPS cell therapy and genome editing therapy. Please see the Job advertisement for details.
  • Event Feb 1, 2023 CiRA Internship program is finally back this summer! Please see this page for details. The deadline for foreign students is March 17th.
  • Award Dec 2-3, 2022 Graduate student Yuto Kita received the Best Poster Award at the JSRM Winter Symposium. Congratulations!
  • Staff Oct 3, 2022 New secretary Yukiko Nakamura joined the lab.
  • Staff July 1, 2022 Matthew joined the lab as a postdocoral reseacher.
  • Event June 15, 2022 Hotta presented at ISSCR 2022 Workshop on Clinical Translation
  • Event June 6-8, 2022 the 7th Annual Meeting of the Japanese Society for Genome Editng was successfully closed with more than 300 perticipitants.
  • Paper May 29, 2022 Collaboration paper with CiRA Foundation is published in Molecular Therapy—Methods & Clinical Development
  • Staff May 20, 2022 Akane enters to the Tokyo Institute of Technology as a master student
  • Staff May 2, 2022 Hotta promoted as Associate Professor.
  • Staff April 1, 2022 Office Assistant Shimpei Uchiyama joined the lab.
  • Staff Jan 31, 2022 Eman moved to Egypt.
  • Paper Dec 8, 2021 LNP delivery of CRISPR-Cas9 into in vivo skeletal muscle was published in Nature Communications.
  • Paper Nov 19, 2021 Protocol paper of efficient genome editing in iPS cells by utilizing Cas9 RNP and ssODN published in STAR Protocols
  • Staff Oct 12, 2021 Technical staff Yoshie Masuda joined the lab.
  • Media Oct 3, 2021 NHK TV program "Science ZERO" about the CRISPR-Cas9 for winning the Nobel Prize 2020 in Chemistry is now on YouTube
  • Paper Sep 10, 2021 Collaboration paper with Nara Medical University in Regenerative Therapy
  • Paper Aug 10, 2021 Collaboration paper with CiRA Yoshida lab in Stem Cell Reports
  • Paper June 15, 2021 Collaboration paper with CiRA Sakurai lab in Cell Reports Medicine
  • Paper May 17, 2021 Collaboration paper with CiRA Kaneko lab in Nature Biomedical Engineering
  • Staff May 6, 2021 Technical staff Akane Ichiki joined the lab.
  • Event Apr 14, 2021 Uploaded the Hotta lab introductory presentation (Japanese only) on YouTube.
  • Staff Apr 1, 2021 Dr. Kojima was promoted as a Program-specific Assistant Professor.
  • Paper Mar 11, 2021 Kagita, Mandy, Xu, and Peter's paper on Cas9 RNP mediated efficient genome editing is now published in Stem Cell Reports. Congratulations!
  • Staff Mar 1, 2021 Technical staff Kuwabara joined the lab. Bang came back from his military service in Korea.
  • Event Mar 1, 2021 9th CiRA Retreat 2020 was held on virtual.
  • Award Dec 25, 2020 Kita was selected as a DC2 Research Fellow of the JSPS. Congratulations!
  • Staff Nov 2, 2020 Dr. Eman Taha from Okayama University has joined the lab.
  • Award Oct 7, 2020 The Novel Prize in Chemistry has been awarded to Drs. Emmanuelle Charpentier and Jennifer A. Doudna. CRISPR-Cas9 is a groundbreaking tool that has revolutionized life sciences and gene therapy applications, and I am very pleased as a researcher in the same field.
  • Event Aug 13, 2020 Hotta gave a video presentation at the KSSCR 2020 Annual Meeting @Seoul.
  • Event July 25, 2020 Hotta gave a web-presentation at the Genome Writers Guild Conference 2020 Virtual
  • Staff July 15, 2020 Dr. Yusuke Kojima from Mayo Clinic has joined the lab.
  • Paper July 14, 2020 Collaboration paper with Dr. Nishinakamura at Kumamoto University published in J Am Soc Nephrol.
  • Paper July 14, 2020 Collaboration paper with CiRA Sakurai lab published in Stem Cell Reports.
  • Paper June 24, 2020 Collaboration paper with CiRA Sakurai lab published in Stem Cell Research.
  • Award June 23, 2020 Our HLA editing paper was selected for the Best of Cell Stem Cell 2019! Please check here.
  • Event May 18-29, 2020 Hotta gave a web presentation at the 19th JSRM Annual Meeting.
  • Award May 18, 2020 Hotta received the Japanese Society for Regenerative Medicine Award.
  • Info April 16 - May 25 The Japanese government has issued a declaration of emergency, due to the COVID-19 pandemic.
  • Staff April 9, 2020 Joseph Lee from the University of Toronto (Canada) join as a master course student.
  • Staff March 31, 2020 Yuya moved to Nagoya University and Akihiro entered to Faculty of Medicine, Yamaguchi University.
  • Award Mar 16, 2020 The CRISPR-Cas3 paper with Drs. Mashimo and Takeda was selected for the Top 50 Life and Biological Sciences Articles in Nature Communications.
  • Paper Mar 13, 2020 Peter's paper on NanoMEDIC delivery of CRISPR-Cas9/gRNA is now published in Nature Communications. Congratulations!
  • Paper Dec 6, 2019 Yuya's novel CRISPR-Cas3 paper was published in Nature Communications. This was a very fruitful collaboration with Dr. Mashimo at the University of Tokyo and Dr. Takeda at Osaka University.
  • Award Nov 27-29, 2019 Huaigeng received the Poster Award at the CiRA International Symposium 2019. Congratulations!
  • Event Nov 13-14, 2019 Hotta presented at SCSS-ISCT Joint Symposium 2019 @Singapore
  • Paper April 1, 2019 Huaigeng's Cell Stem Cell paper was published in print today, and the illustration drawn by Misaki Ouchida from the CiRA PR Office was highlighted on the cover!
  • Staff April 1, 2019 Bang Uikyu from Korea joined the lab as a Master student, however, he had to take a leave from the university for two years to serve for the Korean military. I sincerely hope that the world to be no need for any military forces someday.